Test directory: HCV RNA Gen 1 NS3 Drug Resistance

Ordering Code 4135
Test Name HCV RNA Gen 1 NS3 Drug Resistance
Alias Hepatitis C Viral RNA NS3 Genotype 1 Drug Resistance
Grazoprevir Resistance
HCV NS3 Protease Mutations
NS3 Subtype
Paritaprevir Resistance
Q80K Polymorphism
Simeprevir Resistance
Preferred Specimen Plasma
Preferred Container EDTA, K2 (Lavender)
Other Specimen/Container Serum in Plain (Red)
Optimum Volume 2 mL
Handling Instructions Separate plasma from whole blood within 24 hours of collection by centrifugation at 800-1600 x g for 20 minutes at room temperature. Transfer the plasma to a properly identified, polypropylene screw-cap vial and ship refrigerated or frozen.
Transport Requirements Oahu: Refrigerated
Airline: Frozen
time requirements. Freeze aliquot.
Specimen Stability Ambient: Not Stable
Refrigerated: 3 Days
Frozen: 42 Days
Rejection Criteria Grossly hemolyzed, Grossly Lipemic, Specimens using Heparin or gel separator tubes
Avail. Stat NO
Analytic Time Up to 13 Days
Methodology Polymerase Chain Reaction (PCR); Sequencing
Reference Lab  Quest Diagnostic Lab-NI

Reference range(s)

The reference ranges listed below are valid on this date of June 29, 2025.
Component Age Male Norm Male Critical Low Male Critical High Female Norm Female Critical High Female Critical Low Units Add'l info
HCV NS3 Subtype ALL See report.
Grazoprevir Resistance ALL See report.
Paritaprevir Resistance ALL See report.
Simeprevir Resistance ALL See report.