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Ordering Code	4398
Test Name	Metanephrines, Random Urine
Alias	Normetanephrines, Random Urine
Preferred Specimen	Urine, Random
Preferred Container	Sterile Container
Other Specimen/Container	Random Urine in Clean Container Urine without preservative is acceptable if pH<6 and the sample is shipped frozen.
Optimum Volume	10 mL
Collection Instructions	Patient age & sex required on requisition Patient should avoid caffeine (coffee, tea, energy drinks, etc.), and nicotine (tobacco) for 3 days prior to specimen collection. It is preferable for the patient to be off medications for 3 days prior to collection. Common antihypertensives (diuretics, ACE inhibitors, calcium channel blockers, alpha and beta blockers) cause minimal or no interference. Medications which are alpha agonists (Aldomet), alpha blockers (Dibenzyline) should be avoided 18-24 hours prior to specimen collection.
Handling Instructions	Upon receipt at Central Lab, acidify with 6N HCl to maintain pH below 3 or freeze immediately.
Transport Requirements	Oahu: Refrigerated Airline: Frozen
Specimen Stability	Unpreserved Urine: Ambient and Refrigerated: Unacceptable Frozen: 30 Days Preserved Urine: Ambient: 10 Days Refrigerated: 14 Days Frozen: 90 Days
Rejection Criteria	pH>6 and not frozen, Urine collected with boric acid
Avail. Stat	NO
Analytic Time	Up to 6 Days
Methodology	Kinetic Alkaline Picrate, Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
Reference Lab	Quest Diagnostic Lab-NI

Reference range(s)

The reference ranges listed below are valid on this date of June 29, 2025.