Test directory: Quadruple Screen

Ordering Code 5087
Test Name Quadruple Screen
Alias Quad Screen
MSAFP/HCG Quant/Estriol/Inhibin A
Preferred Specimen Serum
Preferred Container SST (Gold)
Other Specimen/Container Serum in Plain (Red)
Optimum Volume 3 mL
Collection Instructions All pertinent information must be filled in on the
Requisition Form. Specimen must be collected between 15-20 weeks and 6 days gestation.
Transport Requirements Oahu: Refrigerated
Airline: Refrigerated
Specimen Stability Ambient: 8 Hours
Refrigerated: 2 Days
Frozen: 1 Month
Frozen samples should be thawed only once. DO NOT use frost-free freezers.
Rejection Criteria Grossly hemolyzed, Insufficient quantity, Specimen older than stability limits, Gross lipemia, Specimen not collected between 15-20 weeks and 6 days gestation
Avail. Stat NO
Analytic Time Up to 3 Days
Methodology Inhibin A: Enzyme Linked Immunosorbent Assay (ELISA)
Refer to individual tests fro HCG, MSAFP, Estriol.

Reference range(s)

The reference ranges listed below are valid on this date of June 29, 2025.
Component Age Male Norm Male Critical Low Male Critical High Female Norm Female Critical High Female Critical Low Units Add'l info
Gestational Age ALL Wks. See report.
G.A. Based On ALL See report.
Age At Term ALL Yrs. See report.
Weight ALL lbs. See report.
Race ALL See report.
Gestation ALL See report.
Insulin Dependent Diabetic ALL See report.
Smoking Status ALL See report.
Repeat test ALL See report.
FH of NTD ALL See report.
FH of Down Syndrome ALL See report.
AFP ALL ng/mL See report.
MOM ALL <2.5
Beta-HCG, Total ALL IU/mL See report.
MOM ALL 0.26-2.49
Unconjugated Estriol ALL ng/mL See report.
MOM ALL >0.2
Inhibin A, Dimeric ALL pg/ml See report.
MOM ALL <2.0
Down Syndrome Risk Assessment ALL See report.
Down Syndrome Age Risk ALL <1:365
Down Syndrome Screen Risk ALL <1:365
NTD Risk Assessment ALL See report.
NTD Screen Risk ALL <1:484
Trisomy 18 Assessment ALL See report.
Tri18 Screen Risk ALL <1:334
Interpretation ALL See report.