Reference range(s)
The reference ranges listed below are valid on this date of November 21, 2024.
| Component | Age | Male Norm | Male Critical Low | Male Critical High | Female Norm | Female Critical High | Female Critical Low | Units | Add'l info |
|---|---|---|---|---|---|---|---|---|---|
| Teriflunomide (TDM) | ALL | ng/mL | Teriflunomide... Note1 |
Note1:
Teriflunomide is indicated for the treatment of patients with relapsing forms of multiple sclerosis
It takes approximately 3 months to reach steady-state concentrations
Recommended doses of teriflunomide and leflunomide result in a similar range of teriflunomide plasma concentrations. Based on this, the expected therapeutic range is between 18000 ng/mL and 63000 ng/mL
Following completion of an elimination regimen, plasma concentrations should be determined twice at least 14 days apart to verify that concentrations are less than 20 ng/mL. THIS TEST IS NOT MEANT TO MONITOR THE
ELIMINATION OF TERIFLUNOMIDE IN WOMEN OF CHILDBEARING
POTENTIAL WHO DISCONTINUE TERIFLUNOMIDE. The drug carries a black box warning for hepatotoxicity and teratogenicity
See report..