| Ordering Code | 5486 |
|---|---|
| Test Name | Coagulation Mixing Study w/Interp |
| Alias | 1:1 Mix 4:1 Mix Test includes review and interpretation by Pathologist |
| Preferred Specimen | Plasma |
| Preferred Container | Citrate, 3.2% (Lt Blue) |
| Other Specimen/Container | Whole Blood in Citrate, 3.2% (Lt Blue) if testing is done within 4 hours. |
| Optimum Volume | Plasma: 2 mL divided into 2 aliquots |
| Collection Instructions | Draw full tube Mix tube well. |
| Handling Instructions | Double centrifuge to produce platelet-poor plasma, avoid the WBC/platelet buffy layer, separate and freeze at -20 deg C immediately. Do NOT thaw once specimen is frozen. |
| Transport Requirements | Preferred method of transport is frozen plasma. |
| Specimen Stability | Ambient: 4 Hours Refrigerated: Not Stable Frozen: 2 Weeks Plasma |
| Rejection Criteria | Clotted, Contaminated, Hemolyzed, Improperly filled or underfilled tube, Collected in the wrong anticoagulant, Mislabeled, Specimen older than stability limits |
| Avail. Stat | NO |
| Analytic Time | Up to 2 Days |
| Methodology | Clot Detection |
Reference range(s)
The reference ranges listed below are valid on this date of November 22, 2025.
| Component | Age | Male Norm | Male Critical Low | Male Critical High | Female Norm | Female Critical High | Female Critical Low | Units | Add'l info |
|---|---|---|---|---|---|---|---|---|---|
| Protime | ALL | 10.2-12.9 | 10.2-12.9 | secs | |||||
| PT 1:1 Mix | ALL | secs | See report. | ||||||
| PT 1:1 Mix Incubated | ALL | secs | See report. | ||||||
| PTT | ALL | 25.1-36.5 | >= 200.1 | 25.1-36.5 | >= 200.1 | secs | |||
| PTT 1:1 Mix | ALL | secs | See report. | ||||||
| PTT 1:1 Mix Incubated | ALL | secs | See report. | ||||||
| Thrombin Time | ALL | 10.3-16.6 | 10.3-16.6 | secs | |||||
| Fibrinogen | ALL | 200-393 | 200-393 | mg/dL | |||||
| Anti-Xa | ALL | <=0.05 | <=0.05 | IU/mL |
