Test directory: HBV Quant. w/ Reflex to Genotype

Ordering Code5509R
Test NameHBV Quant. w/ Reflex to Genotype
AliasHepatitis B Virus DNA, Quantitative with Reflex to
HBV Genotype
Preferred SpecimenSerum
Preferred ContainerSST (Gold)
Optimum Volume4 mL
Collection InstructionsDraw 2 full SST tubes.
Handling InstructionsSeparate serum from whole blood within 24 hours of collection
Use only polypropylene tubes for aliquot samples
DO NOT thaw once serum is frozen.
Transport RequirementsOahu: Frozen
Airline: Frozen
Specimen StabilityRefrigerated: 6 Days
Frozen: 1 Month
Avail. StatNO
Analytic TimeUp to 7 Days
MethodologyReal time PCR

Reference range(s)

ComponentAgeMale NormMale Critical LowMale Critical HighFemale NormFemale Critical HighFemale Critical LowUnitsAdd'l info

The linear...

The linear range for the cobas (R) HBV for a 500 uL sample processing volume for EDTA plasma and serum is from 10 IU/mL to 1.00E+09 IU/mL with an accuracy within +/-0.24 log10
The lower limit of quantification (LLoQ) is 10 IU/mL

The limit of detection (LoD) of cobas (R) HBV for 500 uL sample processing volume is 6.6 IU/mL for EDTA plasma and 3.5 IU/mL for serum. The same LoD has been verified for genotypes A through H and the predominant precore mutant

Reliable results depend on proper sample collection, storage and handling procedures. Quantitation of HBV DNA is dependent on the number of virus particles present in the samples and may be affected by sample collection methods, patient factors (i.e. age, presence of symptoms), and/or stage of infection
HBV-DNAALL<1.0<1.0Log IU/mL