Test directory: Paraneoplastic Autoantibody Eval

Ordering Code5620
Test NameParaneoplastic Autoantibody Eval
AliasParaneoplastic Autoantibody
Evaluation
Acetylcholine Receptor (Muscle
AChR) Antibodies
ANNA (Antineuronal Nuclear
Antibody)
Preferred SpecimenSerum
Preferred ContainerSST (Gold)
Optimum Volume5 mL
Collection InstructionsSpecimen collection is recommended prior to initiation of immunosuppressant medication or intravenous immunoglobulin (IVIg) treatment. Patient should have no general anesthetic or muscle-relaxant drugs in the previous 24 hours
Radioisotopes, therapeutic or diagnostic, have the potential for assay interference.
Handling InstructionsEnsure that 2 aliquots are sent for testing.
Transport RequirementsOahu: Refrigerated
Airline: Refrigerated
Specimen StabilityAmbient: 3 Days
Refrigerated: 28 Days
Frozen: 28 Days
Rejection CriteriaGrossly hemolyzed, Grossly Lipemic, Grossly Icteric
Avail. StatNO
Analytic TimeUp to 17 Days
MethodologyAChR Ganglionic Neuronal Ab, S Radioimmunoassay (RIA),
Amphiphysin Ab, S Immunofluorescence (IFA),
AGNA-1, S IFA,
ANNA-1, S IFA,
ANNA-2, S IFA,
ANNA-3, S IFA,
CRMP-5-IgG, S IFA,
Neuronal (V-G) K+ Channel Ab, S RIA,
P/Q-Type Calcium Channel Ab RIA,
PCA-1, Alphanumeric titer IFA,
PCA-2, Alphanumeric titer IFA,
PCA-Tr, S IFA
Reference Lab Mayo Medical Lab

Reference range(s)

The reference ranges listed below are valid on this date of January 26, 2022.
ComponentAgeMale NormMale Critical LowMale Critical HighFemale NormFemale Critical HighFemale Critical LowUnitsAdd'l info
AChR Ganglionic Neuronal Ab, SALL<=0.02<=0.02nmol/L
Amphiphysin Ab, SALL<1:240<1:240titer
Anti-Glial Nuclear Ab, Type 1ALL<1:240<1:240titer
Anti-Neuronal Nuclear Ab, Type 1ALL<1:240<1:240titer
Anti-Neuronal Nuclear Ab, Type 2ALL<1:240<1:240titer
Anti-Neuronal Nuclear Ab, Type 3ALL<1:240<1:240titer
CRMP-5-IgG, SALL<1:240<1:240titer
Neuronal (V-G) K+ Channel Ab, SALL<=0.02<=0.02nmol/L
P/Q-Type Calcium Channel AbALL<=0.02<=0.02nmol/L
Purkinje Cell Cytoplas. Ab, Type 1ALL<1:240<1:240titer
Purkinje Cell Cytoplas. Ab, Type 2ALL<1:240<1:240titer
Purkinje Cell Cytoplas. Ab, Type TrALL<1:240<1:240titer