Test directory: Isoniazid

Ordering Code595
Test NameIsoniazid
Preferred SpecimenSerum
Preferred ContainerPlain (Red)
Other Specimen/ContainerPlasma in EDTA, K2 (Lavender)
Optimum Volume1.5 mL
Collection InstructionsDo Not use SST.
Handling InstructionsSeparate and freeze immediately.
Transport RequirementsOahu: Frozen
Airline: Frozen
Specimen StabilityAmbient: 1 Day
Refrigerated: 1 Day
Frozen (-20): 1 Day
Frozen (-70): 30 Months
Rejection CriteriaGel barrier tube, Received ambient at reference laboratory,
Avail. StatNO
Analytic TimeUp to 10 Days
MethodologyHigh Performance Liquid Chromatography/Tandem Mass
Spectrometry (LC/MS/MS)
Reference Lab National Medical Services, Inc.

Reference range(s)

ComponentAgeMale NormMale Critical LowMale Critical HighFemale NormFemale Critical HighFemale Critical LowUnitsAdd'l info


Usual therapeutic range in the treatment of tuberculosis: 1 - 7 mcg/mL. Toxic symptoms are present at approximately 20 mcg/mL and greater. Isoniazid is known to have limited stability in biological specimens which may be concentration and storage condition dependent
Negative or lower than expected results should be interpreted with caution

Analysis by High Performance Liquid Chromatography/Tandem Mass
Spectrometry (LC-MS/MS)

This test was developed and its performance characteristics determined by NMS Labs. It has not been cleared or approved by the US Food and
Drug Administration

See report.