Test directory: Acetaminophen (Tylenol)

Ordering Code701
Test NameAcetaminophen (Tylenol)
Pain Eze
Preferred SpecimenPlasma
Preferred ContainerLithium Heparin PST (Green)
Other Specimen/ContainerSerum in Plain (Red), Serum in SST (Gold)
Optimum Volume0.5 mL
Collection InstructionsThe best indicator of Acetaminophen toxicity is to measure the drug half-life by analyzing a blood level taken 4 hours post-ingestion, then a second level 3-4 hours later. Half lives exceeding 4 hours are consistent with hepatic necrosis.
Handling InstructionsSend aliquot if transport time >24 hours.
Transport RequirementsOahu: Refrigerated
Airline: Frozen
Specimen StabilityAmbient and Refrigerated: 24 hours (Centrifuged, unaliquoted gel separator tubes)
Refrigerated: 7 days (Aliquot)
Frozen: 6 Months (Aliquot)
Rejection CriteriaGrossly hemolyzed, Insufficient quantity, Specimen older than stability limits, Uncentrifuged gel separator tube specimens >2 hours old, Unaliquoted gel separator tube specimens >24 hours old
Avail. StatYES
Analytic Time1 Day
MethodologyHomogenous Enzyme Immunoassay (EMIT)

Reference range(s)

ComponentAgeMale NormMale Critical LowMale Critical HighFemale NormFemale Critical HighFemale Critical LowUnitsAdd'l info
Acetaminophen (Tylenol)ALLTR = 10-30>= 31TR = 10-30>= 31ug/mL