Test directory: Hydroxychloroquine, Serum/Plasma

Ordering Code 7917
Test Name Hydroxychloroquine, Serum/Plasma
Alias Oxychloroquine
PlaquenII
Preferred Specimen Plasma
Preferred Container EDTA, K2 (Lavender)
Other Specimen/Container Serum in Plain (Red)
Optimum Volume 1 mL
Handling Instructions Promptly centrifuge and separate Serum or Plasma
Transport Requirements Oahu: Ambient
Airline: Ambient
Specimen Stability Ambient: 30 Days
Refrigerated: 30 Days
Frozen: 12 Months
Rejection Criteria Gel barrier tube
Avail. Stat NO
Analytic Time 12 Days
Methodology High Performance Liquid Chromatography/Tandem Mass
Spectrometry (LC-MS/MS)
Reference Lab  National Medical Services, Inc.

Reference range(s)

The reference ranges listed below are valid on this date of June 29, 2025.
Component Age Male Norm Male Critical Low Male Critical High Female Norm Female Critical High Female Critical Low Units Add'l info
Hydroxychloroquine ALL ng/mL

Peak plasma...
Peak plasma concentrations of 410 +/- 130 ng/mL were achieved 2.4 hours after a single oral dose of 400 mg hydroxychloroquine (n = 6). Two cases of hydroxychloroquine overdose (20 g each) were successfully treated throughout cardiovascular collapse and had serum concentrations of 14,000 and 26,000 ng/mL

Analysis by High Performance Liquid Chromatography/
Mass Spectrometry (LC-MS/MS)

This test was developed and its performance characteristics determined by NMS Labs. It has not been cleared or approved by the US Food and Drug
Administration

See report.
Note1

Note1:


Peak plasma concentrations of 410 +/- 130 ng/mL were achieved 2.4 hours after a single oral dose of 400 mg hydroxychloroquine (n = 6). Two cases of hydroxychloroquine overdose (20 g each) were successfully treated throughout cardiovascular collapse and had serum concentrations of 14,000 and 26,000 ng/mL

Analysis by High Performance Liquid Chromatography/
Mass Spectrometry (LC-MS/MS)

This test was developed and its performance characteristics determined by NMS Labs. It has not been cleared or approved by the US Food and Drug
Administration

See report..