Test directory: Olanzapine and Metabolite

Ordering Code7959
Test NameOlanzapine and Metabolite
AliasOlanzapine and Metabolite, Serum/Plasma
Symbyax
Preferred SpecimenPlasma
Preferred ContainerEDTA, K2 (Lavender)
Other Specimen/ContainerSerum in Plain (Red)
Optimum Volume1 mL
Handling InstructionsPromptly centrifuge and separate Serum or Plasma
Transport RequirementsOahu: Ambient
Airline: Refrigerated
Specimen StabilityAmbient: 7 Days
Refrigerated: 30 Days
Frozen: 30 Days
Rejection CriteriaGel barrier tube
Avail. StatNO
Analytic Time10 Days
MethodologyHigh Performance Liquid Chromatography/Tandem Mass
Spectrometry (LC-MS/MS)
Reference Lab National Medical Services, Inc.

Reference range(s)

The reference ranges listed below are valid on this date of December 3, 2024.
ComponentAgeMale NormMale Critical LowMale Critical HighFemale NormFemale Critical HighFemale Critical LowUnitsAdd'l info
N-desmethylolanzapineALLng/mL

Schizophrenic...
Schizophrenic patients stabilized with olanzapine at an average daily dose of 14 mg had steady-state desmethylolanzapine plasma concentrations averaging 6.9 +/- 4.7 ng/mL

See report.
Note1
OlanzapineALLng/mL

Recommended...
Recommended antipsychotic range in adults: 20-80 ng/mL plasma
Analysis by High Performance Liquid
Chromatography/Tandem Mass Spectrometry (LC-MS/MS)

This test was developed and its performance characteristics determined by NMS Labs. It has not been cleared or approved by the US Food and
Drug Administration

See report.
Note2

Note1:


Schizophrenic patients stabilized with olanzapine at an average daily dose of 14 mg had steady-state desmethylolanzapine plasma concentrations averaging 6.9 +/- 4.7 ng/mL

See report..

Note2:


Recommended antipsychotic range in adults: 20-80 ng/mL plasma
Analysis by High Performance Liquid
Chromatography/Tandem Mass Spectrometry (LC-MS/MS)

This test was developed and its performance characteristics determined by NMS Labs. It has not been cleared or approved by the US Food and
Drug Administration

See report..