Test directory: Olanzapine and Metabolite

Ordering Code 7959
Test Name Olanzapine and Metabolite
Alias Olanzapine and Metabolite, Serum/Plasma
Symbyax
Preferred Specimen Plasma
Preferred Container EDTA, K2 (Lavender)
Other Specimen/Container Serum in Plain (Red)
Optimum Volume 1 mL
Handling Instructions Promptly centrifuge and separate Serum or Plasma
Transport Requirements Oahu: Ambient
Airline: Refrigerated
Specimen Stability Ambient: 7 Days
Refrigerated: 30 Days
Frozen: 30 Days
Rejection Criteria Gel barrier tube
Avail. Stat NO
Analytic Time 10 Days
Methodology High Performance Liquid Chromatography/Tandem Mass
Spectrometry (LC-MS/MS)
Reference Lab  National Medical Services, Inc.

Reference range(s)

Component Age Male Norm Male Critical Low Male Critical High Female Norm Female Critical High Female Critical Low Units Add'l info
N-desmethylolanzapine ALL ng/mL

Schizophrenic...

Schizophrenic patients stabilized with olanzapine at an average daily dose of 14 mg had steady-state desmethylolanzapine plasma concentrations averaging 6.9 +/- 4.7 ng/mL

See report.
Olanzapine ALL ng/mL

Recommended...

Recommended antipsychotic range in adults: 20-80 ng/mL plasma
Analysis by High Performance Liquid
Chromatography/Tandem Mass Spectrometry (LC-MS/MS)

This test was developed and its performance characteristics determined by NMS Labs. It has not been cleared or approved by the US Food and
Drug Administration

See report.