Test directory: Chromosome, Leukemia/Lymphoma

Ordering Code8333
Test NameChromosome, Leukemia/Lymphoma
AliasChromosome Analysis, Hematologic Disorders
Preferred SpecimenBone marrow, blood (>4% blasts required- see Collection), lymph node, spleen, bone core, or effusion
Preferred ContainerBone marrow or peripheral blood in Sodium Heparin (Green) OR lymph node, spleen, bone core, CSF, or effusion in lymph node transport bottle
Optimum Volume2 mL bone marrow, 3 mL peripheral blood, or 0.5-1 cm(3) tissue biopsy
Collection InstructionsThe requirement of >4% blasts for blood does not apply to cases of CLL, hairy cell leukemia, and some cases of small- cell lymphocytic leukemia (SCLL) or lymphoma, which can be beta-mitogen stimulated. Submit bone marrow or peripheral blood at room temperature using
Leukemia/Lymphoma Specimen Transport Kit (supplied by LabCorp). Submit lymph node, spleen, or bone core at room temperature using
Lymph Node Transport Kit (supplied by LabCorp)
Effusions may be sent in small sterile containers. Specimens should arrive in the laboratory within 48 hours of collection.
Indicate date and time of collection on the test request form.
CULTURING AND RESULT INTERPRETATION. If plasma- enriched MULTIPLE MYELOMA PROFILE (test 510325) is ordered concurrently and sample is not sufficient for both tests, FISH will be prioritized. Please direct any questions regarding this test to customer service at 800-345-4363.
Transport RequirementsOahu: Ambient
Airline: Ambient
Rejection CriteriaHemolysis, Gross contamination, Non-neoplastic cells,
Clotted specimen, Frozen specimen, Fixed specimen,
Improper or too much anticoagulant
Avail. StatNO
Analytic Time9 - 12 Days
MethodologyShort-term cell culture; synchronization; chromosome harvest; G-banding; analysis (20 metaphases) and karyotyping; long-term beta- mitogen cultures in some B-cell leukemias
Reference Lab Accupath Dx Laboratory, Inc.

Reference range(s)

ComponentAgeMale NormMale Critical LowMale Critical HighFemale NormFemale Critical HighFemale Critical LowUnitsAdd'l info
Cells AnalyzedALLSee report.
Cells CountedALLSee report.
Cells KaryotypedALLSee report.
Cytogenetic ResultALLSee report.
Director Review:ALLSee report.
GTG Band Resolution AchievedALLSee report.
InterpretationALLSee report.
PDFALLSee report.
SPEC TYPALLSee report.