Test directory: D-Dimer, Quantitative

Ordering Code 581
Test Name D-Dimer, Quantitative
Alias FDP
FSP
FBP
Thrombo-Wellco Test
Fibrin(Degradation/Split/Breakdown) Products
High Sensitivity D-Dimer
Preferred Specimen Plasma
Preferred Container Citrate, 3.2% (Lt Blue)
Other Specimen/Container Whole Blood in Citrate, 3.2% (Lt Blue) if testing is done within 4 hours.
Optimum Volume Plasma = 1 mL
Collection Instructions Draw full tube
Mix tube well
Handling Instructions If submitting plasma: double centrifuge to produce platelet-poor plasma, avoid the WBC/platelet buffy layer, separate and freeze at -20 deg C immediately. Do NOT thaw once specimen is frozen.
Transport Requirements Preferred method of transport is frozen plasma.
Specimen Stability Ambient: 4 Hours Whole Blood
Ambient: 8 Hours Plasma (Aliquoted)
Refrigerated: Not Stable
Frozen: 2 Weeks Plasma
Rejection Criteria Clotted, Contaminated, Hemolyzed, Improperly filled or underfilled tube, Collected in the wrong anticoagulant,
Mislabeled, Specimen older than stability limits
Avail. Stat YES
Analytic Time 1 Day
Methodology Latex agglutination

Reference range(s)

The reference ranges listed below are valid on this date of May 22, 2025.
Component Age Male Norm Male Critical Low Male Critical High Female Norm Female Critical High Female Critical Low Units Add'l info
D-Dimer, Quantitative ALL <=500 <=500 ng/mL FEU
D-dimer values < or ... D-dimer values < or =500 ng/mL Fibrinogen Equivalent Units (FEU) are normal

This assay may be used in conjunction with clinical pre-test probability to exclude pulmonary embolism (PE) and deep vein thrombosis (DVT). A normal D-dimer result (< or =500 ng/mL FEU) on this assay has a negative predictive value of approximately 97% for the exclusion of acute PE and/or DVT when there is a low or moderate pre-test probability. Increased D-dimer values are abnormal but are not disease specific and may be seen in various states associated with activation of the procoagulant and fibrinolytic systems
Note1

Note1:

D-dimer values < or =500 ng/mL Fibrinogen Equivalent Units (FEU) are normal

This assay may be used in conjunction with clinical pre-test probability to exclude pulmonary embolism (PE) and deep vein thrombosis (DVT). A normal D-dimer result (< or =500 ng/mL FEU) on this assay has a negative predictive value of approximately 97% for the exclusion of acute PE and/or DVT when there is a low or moderate pre-test probability. Increased D-dimer values are abnormal but are not disease specific and may be seen in various states associated with activation of the procoagulant and fibrinolytic systems
.