Test directory: Isoniazid

Ordering Code 595
Test Name Isoniazid
Alias INH
Nydrazid
Preferred Specimen Serum
Preferred Container Plain (Red)
Other Specimen/Container Plasma in EDTA, K2 (Lavender)
Optimum Volume 1.5 mL
Collection Instructions Do Not use SST.
Handling Instructions Separate and freeze immediately.
Transport Requirements Oahu: Frozen
Airline: Frozen
Specimen Stability Ambient: 1 Day
Refrigerated: 1 Day
Frozen (-20): 1 Day
Frozen (-70): 30 Months
Rejection Criteria Gel barrier tube, Received ambient at reference laboratory,
Thawed
Avail. Stat NO
Analytic Time Up to 10 Days
Methodology High Performance Liquid Chromatography/Tandem Mass
Spectrometry (LC/MS/MS)
Reference Lab  National Medical Services, Inc.

Reference range(s)

Component Age Male Norm Male Critical Low Male Critical High Female Norm Female Critical High Female Critical Low Units Add'l info
Isoniazid ALL mcg/mL

Usual...

Usual therapeutic range in the treatment of tuberculosis: 1 - 7 mcg/mL. Toxic symptoms are present at approximately 20 mcg/mL and greater. Isoniazid is known to have limited stability in biological specimens which may be concentration and storage condition dependent
Negative or lower than expected results should be interpreted with caution

Analysis by High Performance Liquid Chromatography/Tandem Mass
Spectrometry (LC-MS/MS)

This test was developed and its performance characteristics determined by NMS Labs. It has not been cleared or approved by the US Food and
Drug Administration

See report.