Test directory: Lead, Blood (Venous)

Ordering Code7756
Test NameLead, Blood (Venous)
Preferred SpecimenWhole Blood
Preferred ContainerTrace Element EDTA (Royal Blue)
Other Specimen/ContainerNone
Optimum Volume7 mL
Transport RequirementsOahu: Refrigerated
Airline: Refrigerated
Specimen StabilityAmbient: Indefinite
Refrigerated: Indefinite
Frozen: Not Stable
Rejection CriteriaClotted, Heparinized, Non-metal free tube
Avail. StatNO
MethodologyQuantitative Inductively Coupled Plasma-Mass Spectrometry
Reference Lab ARUP Laboratories

Reference range(s)

ComponentAgeMale NormMale Critical LowMale Critical HighFemale NormFemale Critical HighFemale Critical LowUnitsAdd'l info
Lead, Blood>=6Y< or = 4.9 ug/dL< or = 4.9 ug/dLug/dL

Analysis ...

Analysis performed by Inductively Coupled Plasma-Mass Spectrometry
(ICP-MS).
 
Elevated results may be due to skin or collection-related
contamination, including the use of a noncertified lead-free
tube. If contamination concerns exist due to elevated levels of
blood lead, confirmation with a second specimen collected in a
certified lead-free tube is recommended.
 
Information sources for blood lead reference intervals and
interpretive comments include the CDC's "Childhood Lead               
Poisoning Prevention: Recommended Actions Based on Blood
Lead Level" and the "Adult Blood Lead Epidemiology and
Surveillance: Reference Blood Lead Levels (BLLs) for Adults in
the U.S." Thresholds and time intervals for retesting, medical
evaluation, and response vary by state and regulatory body.
Contact your State Department of Health and/or applicable
regulatory agency for specific guidance on medical
management recommendations.
 
Group    Concentration    Comment
Children 3.5-19.9 ug/dL   Children under the age of 6
                          years are the most vulnerable
                          to the harmful effects of
                          lead exposure. Environmental
                          investigation and exposure
                          history to identify potential
                          sources of lead. Biological
                          and nutritional monitoring
                          are recommended. Follow-up
                          blood lead monitoring is
                          recommended.
 
         20-44.9 ug/dL    Lead hazard reduction and
                          prompt medical evaluation are
                          recommended. Contact a
                          Pediatric Environmental
                          Health Specialty Unit or
                          poison control center for
                          guidance.
  
         Greater than     Critical. Immediate medical
         44.9 ug/dL       evaluation, including
                          detailed neurological exam is
                          recommended. Consider
                          chelation therapy when
                          symptoms of lead toxicity are
                          present. Contact a Pediatric
                          Environmental Health
                          Specialty Unit or poison
                          control center for
                          assistance.
 
Adult    5-19.9 ug/dL     Medical removal is
                          recommended for pregnant
                          women or those who are trying
                          or may become pregnant.
                          Adverse health effects are
                          possible. Reduced lead
                          exposure and increased blood
                          lead monitoring are
                          recommended.
 
         20-69.9 ug/dL    Adverse health effects are
                          indicated. Medical removal
                          from lead exposure is
                          required by OSHA if blood
                          lead level exceeds 50 ug/dL.
                          Prompt medical evaluation is
                          recommended.
 
         Greater than     Critical. Immediate medical
         69.9 ug/dL       evaluation is recommended.
                          Consider chelation therapy
                          when symptoms of lead
                          toxicity are present.
 
This test was developed and its performance characteristics
determined by ARUP Laboratories. It has not been cleared or
approved by the U.S. Food and Drug Administration. This test
was performed in a CLIA-certified laboratory and is intended
for clinical purposes.
Lead, Blood0-5Y< or = 3.4 ug/dL< or = 3.4 ug/dLug/dL

Analysis ...

Analysis performed by Inductively Coupled Plasma-Mass Spectrometry
(ICP-MS).
 
Elevated results may be due to skin or collection-related
contamination, including the use of a noncertified lead-free
tube. If contamination concerns exist due to elevated levels of
blood lead, confirmation with a second specimen collected in a
certified lead-free tube is recommended.
 
Information sources for blood lead reference intervals and
interpretive comments include the CDC's "Childhood Lead               
Poisoning Prevention: Recommended Actions Based on Blood
Lead Level" and the "Adult Blood Lead Epidemiology and
Surveillance: Reference Blood Lead Levels (BLLs) for Adults in
the U.S." Thresholds and time intervals for retesting, medical
evaluation, and response vary by state and regulatory body.
Contact your State Department of Health and/or applicable
regulatory agency for specific guidance on medical
management recommendations.
 
Group    Concentration    Comment
Children 3.5-19.9 ug/dL   Children under the age of 6
                          years are the most vulnerable
                          to the harmful effects of
                          lead exposure. Environmental
                          investigation and exposure
                          history to identify potential
                          sources of lead. Biological
                          and nutritional monitoring
                          are recommended. Follow-up
                          blood lead monitoring is
                          recommended.
 
         20-44.9 ug/dL    Lead hazard reduction and
                          prompt medical evaluation are
                          recommended. Contact a
                          Pediatric Environmental
                          Health Specialty Unit or
                          poison control center for
                          guidance.
  
         Greater than     Critical. Immediate medical
         44.9 ug/dL       evaluation, including
                          detailed neurological exam is
                          recommended. Consider
                          chelation therapy when
                          symptoms of lead toxicity are
                          present. Contact a Pediatric
                          Environmental Health
                          Specialty Unit or poison
                          control center for
                          assistance.
 
Adult    5-19.9 ug/dL     Medical removal is
                          recommended for pregnant
                          women or those who are trying
                          or may become pregnant.
                          Adverse health effects are
                          possible. Reduced lead
                          exposure and increased blood
                          lead monitoring are
                          recommended.
 
         20-69.9 ug/dL    Adverse health effects are
                          indicated. Medical removal
                          from lead exposure is
                          required by OSHA if blood
                          lead level exceeds 50 ug/dL.
                          Prompt medical evaluation is
                          recommended.
 
         Greater than     Critical. Immediate medical
         69.9 ug/dL       evaluation is recommended.
                          Consider chelation therapy
                          when symptoms of lead
                          toxicity are present.
 
This test was developed and its performance characteristics
determined by ARUP Laboratories. It has not been cleared or
approved by the U.S. Food and Drug Administration. This test
was performed in a CLIA-certified laboratory and is intended
for clinical purposes.