Test directory: Hydroxychloroquine, Serum/Plasma

Ordering Code7917
Test NameHydroxychloroquine, Serum/Plasma
AliasOxychloroquine
PlaquenII
Preferred SpecimenPlasma
Preferred ContainerEDTA, K2 (Lavender)
Other Specimen/ContainerSerum in Plain (Red)
Optimum Volume1 mL
Handling InstructionsPromptly centrifuge and separate Serum or Plasma
Transport RequirementsOahu: Ambient
Airline: Ambient
Specimen StabilityAmbient: 30 Days
Refrigerated: 30 Days
Frozen: 12 Months
Rejection CriteriaGel barrier tube
Avail. StatNO
Analytic Time12 Days
MethodologyHigh Performance Liquid Chromatography/Tandem Mass
Spectrometry (LC-MS/MS)
Reference Lab National Medical Services, Inc.

Reference range(s)

ComponentAgeMale NormMale Critical LowMale Critical HighFemale NormFemale Critical HighFemale Critical LowUnitsAdd'l info
HydroxychloroquineALLng/mL

Peak plasma...

Peak plasma concentrations of 410 +/- 130 ng/mL were achieved 2.4 hours after a single oral dose of 400 mg hydroxychloroquine (n = 6). Two cases of hydroxychloroquine overdose (20 g each) were successfully treated throughout cardiovascular collapse and had serum concentrations of 14,000 and 26,000 ng/mL

Analysis by High Performance Liquid Chromatography/
Mass Spectrometry (LC-MS/MS)

This test was developed and its performance characteristics determined by NMS Labs. It has not been cleared or approved by the US Food and Drug
Administration

See report.