Test directory: Sequential 1

Ordering Code8340
Test NameSequential 1
AliasDown Syndrome
Nuchal Translucency (NT)
PAPP-A
Preferred SpecimenSerum
Preferred ContainerSST (Gold)
Optimum Volume3 mL
Collection InstructionsCollect in serum separator tube with gel barrier. Allow blood to clot, avoiding hemolysis. Separate serum from cells by centrifugation. Transport spun tube to testing laboratory. Pour off is not advised. Maternal serum specimens must be drawn prior to amniocentesis to avoid contamination with fetal blood.
Handling InstructionsFor test inquiries, call CMBP genetic services at 800-345-4363. Client must provide fetal nuchal translucency (NT) measurement and crown rump length measurement. The NT measurement must be performed by a sonographer credentialed by the Fetal Medicine Foundation or other equivalent entity. The sonographer's credential/certification number must be provided. The following information also must be provided: patient's race, patient's weight, patient's date of birth, patient's insulin- dependent diabetic status, and the number of fetuses. Also indicate patient history (i.e. prior Down syndrome pregnancy, ultrasound anomalies). Complete information is necessary to interpret the test. Patient information may be provided to the laboratory using the Maternal
Prenatal Screening requisition 0900. Serum testing is provided from 10.0 to 14.0 weeks of gestation. NT can be assessed when the CRL is 45 to 84 mm.
Transport RequirementsOahu: Ambient
Airline: Ambient
Specimen StabilityAmbient: 7 Days
Refrigerated: 14 Days
Frozen: 14 Days
Rejection CriteriaGross hemolysis, Gross lipemia, Quantity not sufficient for analysis, Improper specimen type
Avail. StatNO
Analytic Time4 - 7 Days
MethodologyChemiluminescent immunoassay immunoassay (EIA)
Reference Lab Esoterix Genetic Laboratories, LLC

Reference range(s)

The reference ranges listed below are valid on this date of April 19, 2024.
ComponentAgeMale NormMale Critical LowMale Critical HighFemale NormFemale Critical HighFemale Critical LowUnitsAdd'l info
Additional USALLSee report.
CRL ScanALLSee report.
CRL Scan Twin BALLSee report.
Crown Rump LengthALLSee report.
Crown Rump Length Twin BALLSee report.
Down SyndromeALLSee report.
Down SyndromeALLSee report.
Down Syndrome InterpretationALLSee report.
Gest. Age on Collection DateALLSee report.
hCG MoMALLSee report.
hCG ValueALLSee report.
Maternal Age at EDDALLSee report.
Note:ALLSee report.
NT MoM Twin BALLSee report.
NT Twin BALLSee report.
Nuchal Translucency (NT)ALLSee report.
Nuchal Translucency MoMALLSee report.
Number of FetusesALLSee report.
PAPP-A MoMALLSee report.
PAPP-A ValueALLSee report.
PDFALLSee report.
RaceALLSee report.
ResultsALLSee report.
Sonographer ID#ALLSee report.
Submit Part 2 Sample UsingALLSee report.
Test Results:ALLSee report.
Trisomy 18ALLSee report.
Trisomy 18ALLSee report.
Trisomy 18 InterpretationALLSee report.
WeightALLSee report.