Test directory: Sequential 1

Ordering Code 8340
Test Name Sequential 1
Alias Down Syndrome
Nuchal Translucency (NT)
PAPP-A
Preferred Specimen Serum
Preferred Container SST (Gold)
Optimum Volume 3 mL
Collection Instructions Collect in serum separator tube with gel barrier. Allow blood to clot, avoiding hemolysis. Separate serum from cells by centrifugation. Transport spun tube to testing laboratory. Pour off is not advised. Maternal serum specimens must be drawn prior to amniocentesis to avoid contamination with fetal blood.
Handling Instructions For test inquiries, call CMBP genetic services at 800-345-4363. Client must provide fetal nuchal translucency (NT) measurement and crown rump length measurement. The NT measurement must be performed by a sonographer credentialed by the Fetal Medicine Foundation or other equivalent entity. The sonographer's credential/certification number must be provided. The following information also must be provided: patient's race, patient's weight, patient's date of birth, patient's insulin- dependent diabetic status, and the number of fetuses. Also indicate patient history (i.e. prior Down syndrome pregnancy, ultrasound anomalies). Complete information is necessary to interpret the test. Patient information may be provided to the laboratory using the Maternal
Prenatal Screening requisition 0900. Serum testing is provided from 10.0 to 14.0 weeks of gestation. NT can be assessed when the CRL is 45 to 84 mm.
Transport Requirements Oahu: Ambient
Airline: Ambient
Specimen Stability Ambient: 7 Days
Refrigerated: 14 Days
Frozen: 14 Days
Rejection Criteria Gross hemolysis, Gross lipemia, Quantity not sufficient for analysis, Improper specimen type
Avail. Stat NO
Analytic Time 4 - 7 Days
Methodology Chemiluminescent immunoassay immunoassay (EIA)
Reference Lab  Esoterix Genetic Laboratories, LLC

Reference range(s)

The reference ranges listed below are valid on this date of June 29, 2025.
Component Age Male Norm Male Critical Low Male Critical High Female Norm Female Critical High Female Critical Low Units Add'l info
Additional US ALL See report.
CRL Scan ALL See report.
CRL Scan Twin B ALL See report.
Crown Rump Length ALL See report.
Crown Rump Length Twin B ALL See report.
Down Syndrome ALL See report.
Down Syndrome ALL See report.
Down Syndrome Interpretation ALL See report.
Gest. Age on Collection Date ALL See report.
hCG MoM ALL See report.
hCG Value ALL See report.
Maternal Age at EDD ALL See report.
Note: ALL See report.
NT MoM Twin B ALL See report.
NT Twin B ALL See report.
Nuchal Translucency (NT) ALL See report.
Nuchal Translucency MoM ALL See report.
Number of Fetuses ALL See report.
PAPP-A MoM ALL See report.
PAPP-A Value ALL See report.
PDF ALL See report.
Race ALL See report.
Results ALL See report.
Sonographer ID# ALL See report.
Submit Part 2 Sample Using ALL See report.
Test Results: ALL See report.
Trisomy 18 ALL See report.
Trisomy 18 ALL See report.
Trisomy 18 Interpretation ALL See report.
Weight ALL See report.